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The pH decreases along the duct from pH 7.2 to 6.0 or below, depending on the spider species,. Acidic Residues Control the Dimerization of the N-terminal Domain of Black Widow Spiders' Major.


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ฮฑ-Latrotoxin is a presynaptic neurotoxin isolated from the venom of the black widow spider Latrodectus tredecimguttatus.It exerts toxic effects in the vertebrate central nervous system by depolarizing neurons, by increasing [Ca 2+] i and by stimulating uncontrolled exocytosis of neurotransmitters from nerve terminals. The actions of ฮฑ-latrotoxin are mediated, in part, by a GTP-binding.


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Black Widow Spider Classification. Scientific Name: Latrodectus sp. Common Name: Black Widow Spider. Latin Meaning: "Biting in secret" The spider got its name from the belief that the female consumes the male after mating thus making her a widow, the black part comes from the black color of the spiders body. Domain- Eukarya.


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Description The eye arrangement of spiders in the genus Latrodectus Female widow spiders are typically dark brown or a shiny black in colour when they are full grown, usually exhibiting a red or orange hourglass on the ventral surface (underside) of the abdomen; some may have a pair of red spots or have no marking at all.


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Besides the main interaction between the plug-domain of protomer A and ARs 1-6 of protomer B,. Holz, G. G. & Habener, J. F. Black widow spider alpha-latrotoxin: a presynaptic neurotoxin that.


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The black house spider or common black spider ( Badumna insignis) is a common species of cribellate Australian spider, introduced to New Zealand and Japan. A closely related species, Badumna longinqua, the grey house spider, has a similar distribution, but has also been introduced to the Americas. [2]


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Fig. 6: Phylogenetic analysis and protein domain structure of toxin gene. Z. et al. Chromosome-level genome assembly of the black widow spider Latrodectus elegans illuminates composition and.


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The white widow spider ( Latrodectus pallidus) can be found in North Africa, Central Asia, and the Middle East. The button spider ( Latrodectus indistinctus) is one of several widow spiders native to South Africa. The adult female black widow spider is approximately 2 cm in length and shiny black with a red-orange hourglass or spot on the.


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Spiders ( order Araneae) are air-breathing arthropods that have eight limbs, chelicerae with fangs generally able to inject venom, [2] and spinnerets that extrude silk. [3] They are the largest order of arachnids and rank seventh in total species diversity among all orders of organisms.


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Besides the main interaction between the plug-domain of protomer A and ARs 1-6 of protomer B,. The effect of the purified major protein factor (alpha-latrotoxin) of black widow spider venom on the release of acetylcholine and norepinephrine from mouse cerebral cortex slices. Brain Res. 1978; 139:190-196.


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Latrodectus hesperus, the western black widow spider or western widow, is a venomous spider species found in western regions of North America. The female's body is 14-16 mm (1/2 in) in length and is black, often with an hourglass -shaped red mark on the lower abdomen. This "hourglass" mark can be yellow, and on rare occasions, white.


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A French murderer who was captured in the US before being extradited to his homeland, it was thought Jules Rey died imprisoned in a dungeon, but he instead had only gone blind and, after becoming friends with the spiders in his cell, later surfaced as the Black Spider, swearing vengeance on those that helped convict him. His methods were brutal enough to make even his henchmen get creeped out.


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Kingdom Animalia Phylum Arthropoda Class Arachnida Order Araneae Family Theridiidae Genus Latrodectus Scientific Name Latrodectus Read our Complete Guide to Classification of Animals. Black Widow Spider Conservation Status Least Concern Black Widow Spider Locations Africa Asia Central-America Eurasia Europe North-America Oceania


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These residues were replaced in the amino-terminal domain (NRN1 L.h.) of MaSp1 of the black widow spider (Latrodectus hesperus) by the non-titratable analogues asparagine and glutamine to.


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Background Black widow spiders are infamous for their neurotoxic venom, which can cause extreme and long-lasting pain. This unusual venom is dominated by latrotoxins and latrodectins, two protein families virtually unknown outside of the black widow genus Latrodectus, that are difficult to study given the paucity of spider genomes. Using tissue-, sex- and stage-specific expression data, we.


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The stereotypical black widow is a shiny, round, black spider with a red hourglass mark on its ventral side (belly). Mature female black widows present this appearance. They typically also have a red or orange patch above their spinnerets. Male black widows are much smaller than females, with elongated purple, gray, or black bodies, white.

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